It can add/remove up to 10% fuel. In fact, there is an entire 8x8 fuel map just for the long term fuel trim that is dynamically updated by the ECU* while driving. This is part of the 'self-learn' that is saved while the vehicle is off, and can be reset with Consult tools.
* - On all of the large injector tunes that I have seen the O2 feedback system doesn't work properly due to certain ECU parameters not being re-adjusted correctly for the bigger injectors. This causes the long-term fuel trim to malfunction under certain operating conditions.